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Evidence-based GLP-1 & peptide discussion since 2023
Forumsβ€ΊLab Results & Biomarkersβ€ΊSHBG changes during weight loss on GLP-1 β€” need advice β€Ί Page 4

SHBG changes during weight loss on GLP-1 β€” need advice

TirzTom Thu, Feb 8, 2024 at 2:05 AM 53 replies 3,010 viewsPage 4 of 11
JakeSmashed95
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Feb 8, 2024 at 7:45 AM#16

Congrats carl_compliance!! Keep going β€” you're doing incredible. πŸŽ‰

26 19Dr.PainCLE, mike_mealprep, NicoleRaleigh and 23 others
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BiostatsBrad
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Feb 8, 2024 at 8:02 AM#17

TirzTom's experience with SHBG changes during resonates deeply with mine. I went through almost the identical process β€” starting dose, titration timeline, side effects, everything.

The main difference: I had more GI issues initially. But the overall trajectory has been remarkably similar. Down 45 lbs in 10 months.

One thing I would add that TirzTom did not mention: insurance coverage was a major hurdle.

5 17Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 2 others
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wanda_boise
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Feb 8, 2024 at 8:19 AM#18

Bookmarked πŸ“Œ The SHBG changes during info in this thread is essential. Coming back to this for sure.

Last edited: Feb 8, 2024 at 1:19 PM
37 24pam_columbus, nick_SD_fit, ben_calgary and 34 others
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newstart_MO
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Feb 8, 2024 at 8:36 AM#19

Clinical perspective on SHBG changes during weight loss on GLP-1:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows β€” and what I see in practice β€” is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Feb 8, 2024 at 2:36 PM
46 11TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 43 others
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stefan_berlin
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Feb 8, 2024 at 8:53 AM#20

Subscribing to this thread. SHBG changes during is exactly what I've been researching. πŸ™

24 13TrialTracker_MD, JennaRN, LabKate and 21 others
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