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ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 4

LC-MS/MS vs HPLC for peptide analysis — November 2025

HealthEcon_DC Tue, Nov 18, 2025 at 8:01 PM 29 replies 1,356 viewsPage 4 of 6
oliver_london
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London, UK
Nov 19, 2025 at 1:41 AM#16

Just wanted to say — for anyone reading this LC-MS/MS vs HPLC for thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

Last edited: Nov 19, 2025 at 2:41 AM
4 7Admin, Dr.Martinez, mike_mod and 1 other
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tom_AK
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Jan 2026
Anchorage, AK
Nov 19, 2025 at 1:58 AM#17

100%. My provider said the same thing about LC-MS/MS vs HPLC for.

40 11VanRx_Mike, steve_okc, dave_SLC and 37 others
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WendyG_ATL
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Georgia
Nov 19, 2025 at 2:15 AM#18

+1 to SandraNC_45. Especially the point about "I know it is not exactly on-topic but it..." — I have seen the same in my own experience with LC-MS/MS vs HPLC for.

50 2traveltech_sara, AttorneyGrant, DebRD_ATL and 47 others
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Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

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PharmacoVig_BOS
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Nov 19, 2025 at 2:32 AM#19

Following this thread closely. LC-MS/MS vs HPLC for is something I'm actively working through.

Last edited: Nov 19, 2025 at 5:32 AM
48 11kate.chem, DataDave, Dr.GutHealth and 45 others
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mark_tokyo
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Jun 2024
Tokyo, JP
Nov 19, 2025 at 2:49 AM#20

+1 to laura_annarbor. Especially the point about "Dad of 2 checking in — I started at 277 ..." — I have seen the same in my own experience with LC-MS/MS vs HPLC for.

Last edited: Nov 19, 2025 at 5:49 AM
24 21TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 21 others
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