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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsHas anyone dealt with one hundred pounds down lets gooo? Page 5

Has anyone dealt with one hundred pounds down lets gooo?

DanielChem_CHI Tue, Apr 15, 2025 at 5:09 PM 25 replies 1,966 viewsPage 5 of 5
wendy_avl
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Oct 2024
Asheville, NC
Apr 16, 2025 at 12:14 AM#21

BethLabQueen — that is really helpful context on Has anyone dealt with one. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

43 18SleepFixSam, PurityPaulOR, MaxMetOK and 40 others
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BariatricNurseD
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Feb 2024
Dallas, TX
Online
Apr 16, 2025 at 12:31 AM#22

To answer wei_SG's question specifically:

From a clinical standpoint, Has anyone dealt with one is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

Last edited: Apr 16, 2025 at 5:31 AM
30 7roxy_nash, tony_orlando, Dr.NephBHM_UK and 27 others
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KetoKyle
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Jul 2024
Utah
Apr 16, 2025 at 12:48 AM#23

Thank you wendy_avl! This is incredibly helpful. Taking this to my next appointment. 🙏

22 14pat_auckland, Dr.GastroMayo, JakeBK_lifts and 19 others
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dan_philly
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Jul 2024
Philadelphia, PA
Apr 16, 2025 at 1:05 AM#24

Relevant to Has anyone dealt with one — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

16 18Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 13 others
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TinaHashiRN
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Sep 2024
Raleigh, NC
Apr 16, 2025 at 1:22 AM#25

Slightly tangential to Has anyone dealt with one but wendy_avl reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

23 7MikeNYC_runner and 20 others
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