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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with mash resolution without worsening fibrosis? Page 3

Has anyone dealt with mash resolution without worsening fibrosis?

KevinCompounds Thu, Oct 31, 2024 at 11:40 AM 45 replies 2,606 viewsPage 3 of 9
james_edin
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Sep 2024
Edinburgh, UK
Oct 31, 2024 at 3:55 PM#11

ricardo_MIA — wow. This community is amazing.

30 8mona_PHX, andrew_nyc, Dr.EndoEP and 27 others
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PurityPaulOR
Senior Member
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Mar 2024
Oregon
Oct 31, 2024 at 4:12 PM#12

Slightly tangential to Has anyone dealt with but KevinCompounds reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Oct 31, 2024 at 7:12 PM
35 18MikeNYC_runner and 32 others
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mia_MS2
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Jun 2026
Ann Arbor, MI
Oct 31, 2024 at 4:29 PM#13

Thanks for sharing this, KevinCompounds. A few questions about your Has anyone dealt experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

4 8dave_SLC, FDA_TrackerJim, ricardo_MIA and 1 other
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KevinCompounds
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Dec 2023
Nevada
Oct 31, 2024 at 4:46 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer PurityPaulOR: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

44 8BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 41 others
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lisa_labSD
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Oct 2024
San Diego, CA
Oct 31, 2024 at 5:03 PM#15

Relevant to Has anyone dealt with mash — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

32 15cory_ATX, lori_vegas, Dr.PulmRoch and 29 others
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