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ForumsCOA & Analytical TestingMass spectrometry for peptide identity verification — March 2026 Page 3

Mass spectrometry for peptide identity verification — March 2026

Dr.ObesityMed Thu, Apr 30, 2026 at 8:44 AM 29 replies 706 viewsPage 3 of 6
DerekSJ_a1c
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San Jose, CA
Apr 30, 2026 at 12:59 PM#11

VanRx_Mike — wow. This community is amazing.

1 21adam_van
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TomFromTexas
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May 2024
Austin, TX
Apr 30, 2026 at 1:16 PM#12

Slightly tangential to Mass spectrometry for but Dr.ObesityMed reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Apr 30, 2026 at 3:16 PM
32 16Dr.NateNeph, PharmD_Rodriguez, julia.endo and 29 others
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cory_ATX
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2,123
Jul 2024
Austin, TX
Apr 30, 2026 at 1:33 PM#13

Thanks for sharing this, Dr.ObesityMed. A few questions about your Mass spectrometry experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Mass spectromet?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

42 19mona_PHX, andrew_nyc, Dr.EndoEP and 39 others
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Dr.ObesityMed
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Nov 2023
Denver, CO
Online
Apr 30, 2026 at 1:50 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Mass spectrometry for.

To answer TomFromTexas: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

34 6PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 31 others
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Dr.GutHealth
Senior Member
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Mar 2024
Minnesota
Apr 30, 2026 at 2:07 PM#15

Relevant to Mass spectrometry for peptide — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

1 2MikeKY_noInsulin
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