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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionHIIT vs LISS cardio on GLP-1 — looking for input

HIIT vs LISS cardio on GLP-1 — looking for input

mark_tokyo Sat, Aug 16, 2025 at 11:20 AM 39 replies 1,657 viewsPage 1 of 8
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mark_tokyo
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Tokyo, JP
Aug 16, 2025 at 12:45 PM#1

Hot take incoming: hiit vs liss cardio on glp-1.

I know this is controversial here but I think the conventional wisdom on this topic might be overly simplistic. Before you grab your pitchforks, hear me out.

My argument is based on conversations with my provider who has a different perspective.

Change my mind. Seriously — I want to be wrong about this if I am.

4 9pete_manc_UK, anna.melb_AU, mark_tokyo and 1 other
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anders_CPH
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Copenhagen, DK
Aug 16, 2025 at 1:02 PM#2

To answer the question about HIIT vs LISS cardio on GLP-1 looking for input — in my experience this comes down to a few key factors.

I have been dealing with this for almost 2 years now, and what I have found is that individual responses really do vary. That said, the general consensus on HIIT vs LISS cardio on GLP-1 seems solid.

What specifically worked for me: combining medication with structured exercise. I would suggest mark_tokyo try the same approach and reporting back.

3 18MariaRD, AussieAnna, BethLabQueen
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LabKate
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Aug 16, 2025 at 1:19 PM#3

anders_CPH nailed it. Building on that — HIIT vs LISS cardio on GLP-1 is something I discuss with my PCP regularly, and their clinical perspective aligns with what anders_CPH described.

One thing I would add: the first few weeks are not representative of long-term results.

Last edited: Aug 16, 2025 at 4:19 PM
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SkepticalSean
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Maine
Aug 16, 2025 at 1:36 PM#4

Subscribing to this thread. HIIT vs LISS cardio on is exactly what I've been researching. 🙏

43 6tammy_FL, Dr.LipidDallas, alex_tucson and 40 others
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julia.endo
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Cincinnati, OH
Aug 16, 2025 at 1:53 PM#5

Clinical perspective on HIIT vs LISS cardio on GLP-1 looking:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

30 20chris_chi24, tampaLisa73, KarenAZ_mom and 27 others
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