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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementThrew up at work today - do I tell my boss why?

Threw up at work today - do I tell my boss why?

NurseAsh_DET Fri, Apr 10, 2026 at 1:24 AM 7 replies 614 viewsPage 1 of 2
NurseAsh_DET
Member
356
1,567
Sep 2024
Detroit, MI
Apr 10, 2026 at 2:49 AM#1

Hi all, brand new here. My doctor just prescribed semaglutide and I have a question about threw up at work today -.

Sorry if this has been asked before — I did try searching but the amount of information here is overwhelming (in a good way). I am on week 2 and everything is new to me.

Any guidance appreciated. You all seem really knowledgeable and I am glad I found this community.

31 22FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 28 others
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SarahChen_PharmD
VIP Member
4,567
22,341
Dec 2023
San Diego, CA
Apr 10, 2026 at 3:06 AM#2

NurseAsh_DET's experience with Threw up at work today - resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 50 lbs in 5 months.

One thing I would add that NurseAsh_DET did not mention: the mental health improvements were just as significant.

34 6NurseKim_ATL, paul_denver, TinaHashiRN and 31 others
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JenMemphis
Member
267
1,234
Jan 2025
Memphis, TN
Apr 10, 2026 at 3:23 AM#3

Thanks for sharing this, NurseAsh_DET. A few questions about your Threw up at work experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Threw up at?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

22 1NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 19 others
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NurseAsh_DET
Member
356
1,567
Sep 2024
Detroit, MI
Apr 10, 2026 at 3:40 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Threw up at work today -.

To answer JenMemphis: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Apr 10, 2026 at 9:40 AM
43 8labquiet_amy, emily_PDX, Dr.SleepRoch and 40 others
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labquiet_amy
Senior Member
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6,789
Mar 2024
Cambridge, MA
Apr 10, 2026 at 3:57 AM#5

Relevant to Threw up at work today - do I — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

5 17pete_manc_UK, anna.melb_AU, mark_tokyo and 2 others
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