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ForumsOral GLP-1 AgonistsOral semaglutide 50mg (Rybelsus HD) — 12 month update Page 6

Oral semaglutide 50mg (Rybelsus HD) — 12 month update

LibrarianMeg Thu, May 30, 2024 at 6:09 AM 44 replies 2,300 viewsPage 6 of 9
ricardo_MIA
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May 30, 2024 at 2:39 PM#26

This thread is incredible for Oral semaglutide info. Better than most online groups.

1 5JakeSmashed95
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TirzTom
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May 30, 2024 at 2:56 PM#27
LeilaHI said:
I started my GLP-1 journey in October 2024 at 289 lbs with prediabetes and hypertension

Gonna push back on this one. Oral semaglutide 50mg (Rybelsus HD) is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

Last edited: May 30, 2024 at 6:56 PM
41 20tom_AK, josh_phd_bmore, roxy_nash and 38 others
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Dr.SportsMedIN
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Indianapolis, IN
May 30, 2024 at 3:13 PM#28

Want to share my personal experience related to Oral semaglutide 50mg since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 250 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 80 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Oral semaglutide aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: May 30, 2024 at 8:13 PM
15 24adam_van, Dr.SurgeonPGH, rachel_ABQ and 12 others
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DeniseRN_TPA
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Aug 2024
Tampa, FL
May 30, 2024 at 3:30 PM#29

Saving this for reference. Quality thread.

22 11LindaRN_retired, tommy_boulder, hyun_seoul and 19 others
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ChrisMacros
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Sep 2024
Michigan
May 30, 2024 at 3:47 PM#30

ricardo_MIA — that is really helpful context on Oral semaglutide 50mg. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: May 30, 2024 at 6:47 PM
42 17bri_stats, pete_manc_UK, anna.melb_AU and 39 others
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