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ForumsOral GLP-1 AgonistsOrforglipron food interaction profile — 12 month update Page 6

Orforglipron food interaction profile — 12 month update

hyun_seoul Sun, Mar 16, 2025 at 3:01 AM 33 replies 2,175 viewsPage 6 of 7
SleepDoc_PDX
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Sep 2024
Portland, OR
Mar 16, 2025 at 11:31 AM#26

Slightly tangential to Orforglipron food but wei_SG reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

24 24pete_nash, hank_denver, carlos_SATX and 21 others
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dan_philly
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Jul 2024
Philadelphia, PA
Mar 16, 2025 at 11:48 AM#27

Saving this for reference. Quality thread.

Last edited: Mar 16, 2025 at 2:48 PM
27 3AmyNC_wife, SkepticalSean, Dr.CardioMD and 24 others
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mike_mealprep
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Jul 2024
Chicago, IL
Mar 16, 2025 at 12:05 PM#28

Want to share my personal experience related to Orforglipron food interaction since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 269 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 69 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Orforglipron food aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Mar 16, 2025 at 6:05 PM
20 5Dr.AddMedPHL, newstart_MO, mia_MS2 and 17 others
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lucas_SP_BR
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456
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Jun 2024
São Paulo, BR
Mar 16, 2025 at 12:22 PM#29

Relevant to Orforglipron food interaction — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 245 → 115 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

30 15KarenAZ_mom, zoe_NC, Dr.ObesityLA and 27 others
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Dr.DermMIA
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May 2024
Miami, FL
Mar 16, 2025 at 12:39 PM#30

Want to share my personal experience related to Orforglipron food interaction since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 286 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 76 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Orforglipron food aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Mar 16, 2025 at 2:39 PM
5 9SurmountFan_IN, PeptideChemSF, A1cHero_PHX and 2 others
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