🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesHas anyone dealt with got off metformin for the first time in 8 years - crying happy tears?

Has anyone dealt with got off metformin for the first time in 8 years - crying happy tears?

AmyNC_wife Fri, Apr 19, 2024 at 2:18 AM 10 replies 2,066 viewsPage 1 of 2
This thread is more than 26 months old. Information may be outdated. Consider searching for more recent discussions.
AmyNC_wife
Member
634
2,890
Jun 2024
North Carolina
Apr 19, 2024 at 3:43 AM#1

Update on my situation with has anyone dealt with got off — wanted to follow up since some of you asked.

3 weeks since my last post and things have improved significantly. Here is what happened:

Talked to my endo about the concerns raised in my previous thread and they agreed with the community advice.

Full details below. Thanks to everyone who responded last time — your input genuinely made a difference.

6 22JessicaM_2024, TomFromTexas, mike.trainer_LA and 3 others
Reply Quote Save Share Report
julia.endo
Senior Member
1,890
9,012
Feb 2024
Cincinnati, OH
Apr 19, 2024 at 4:00 AM#2

AmyNC_wife's experience with Has anyone dealt with got resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 62 lbs in 7 months.

One thing I would add that AmyNC_wife did not mention: the mental health improvements were just as significant.

Last edited: Apr 19, 2024 at 10:00 AM
35 18mark_tokyo, hans_munich, jason_sac26 and 32 others
Reply Quote Save Share Report
mark_tokyo
Member
456
1,890
Jun 2024
Tokyo, JP
Apr 19, 2024 at 4:17 AM#3

Thanks for sharing this, AmyNC_wife. A few questions about your Has anyone dealt experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Apr 19, 2024 at 7:17 AM
9 23LibrarianMeg, bri_stats, pete_manc_UK and 6 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
AmyNC_wife
Member
634
2,890
Jun 2024
North Carolina
Apr 19, 2024 at 4:34 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with got.

To answer mark_tokyo: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

2 15Dr.NateNeph, PharmD_Rodriguez
Reply Quote Save Share Report
jason_paloalto
Member
212
890
Nov 2024
Palo Alto, CA
Apr 19, 2024 at 4:51 AM#5

Relevant to Has anyone dealt with got off — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 195 → 95 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

15 0Dr.EndoEP, GraceAZ_72, carl_compliance and 12 others
Reply Quote Save Share Report

Similar Threads

SUSTAIN-6 to SELECT — the cardiovascular evidence timeline14 replies
GLP-1 and insulin resistance — HOMA-IR improvement data17 replies
Metabolic syndrome reversal criteria — how GLP-1 addresses all 55 replies
A1C target achievement rates — sema vs tirz comparison8 replies
SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design3 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register